Destroy first Spider
Destroy 10 Spiders
Destroy 100 Spiders
Destroy 1,000 Spiders
Destroy 10,000 Spiders
Destroy 10 Spiders with each weapon on a single run
Destroy 10 Spiders with each weapon using Overdrive on a single run
Deflect damage with Dash 10 times in a single run
Destroy all Radiant Spiders in a single run
Complete a Loop with at least one Challenge
Complete a Loop with at least five Challenges
Complete a Loop in Normal difficulty
Complete a Loop in Hard difficulty
Complete a Loop in Extreme difficulty
Complete a Loop in Nightmare difficulty
Earn rampage bonus for each wave in Survival
Bit by a Radiant Spider
Cause Rift to blink
Harvest 20 Spiders in a single run
Destroy 100 Spiders with bullet weapons in a single run
Destroy 100 Spiders with energy weapons in a single run
Destroy 100 Spiders with explosive weapons in a single run
Destroy 100 Spiders with fire weapons in a single run
Lash 100 Spiders in a single run
Destroy 100 Spiders with special weapons in a single run
Complete a Lash & Dash Chain
Complete all tutorials
Enable tutorials
Complete Level 5 in Daily Run
Open the soundtrack player
Destroy 100 Spiders with indirect explosions in a single run
Destroy 100 Spiders with Overdrive in a single run
Destroy 1,000 Spiders with Overdrive in a single run
Keep Blaster for an entire run
Get 1,000,000 points in a single run
Get 1,000,000,000 points in a single run
Get 1,000,000,000,000 points in a single run
Destroy 100 Spiders with Scythe in a single run
Destroy three or more Spiders with one shot
Defeat Fred
Win duel against Spite
Win duel against Survive
Win duel against Sacrifice
Defeat Spite as the final boss
Defeat Survive as the final boss
Defeat Sacrifice as the final boss
Become Spite
Become Survive
Become Sacrifice
Defeat Spite, Survive and Sacrifice as both the mid and final bosses
Get the Sharpshooter bonus
Select the bonus Corruption ending
Complete 15 Arena levels
Complete 30 Arena levels
Complete all 60 Arena levels
Survive over 60 seconds without shooting
Survive over 60 seconds without shooting or taking damage