Earn all trophies
Return to the station 5 times
Discover a secret room for the first time
Steal from a shop
Beat a corrupted guardian
Meet with the king of all frogs
Pet the cat a total of 10 times
Get a Synergy
Beat the Gazing Grove
Beat the Gazing Grove without taking a single hit
Defeat Denial, by shooting them while they have their eye open
Beat the Fungated Funnels
Beat the Fungated Funnels without taking a single hit
Defeat Anger without defeating any other enemies during the fight
Beat the Hollow Hives
Beat the Hollow Hives without taking a single hit
Beat the Arid Athenaeum
Beat the Arid Athenaeum without taking a single hit
Defeat Bargaining while they are spinning on the ground
Beat the Somber Sepulcher
Beat the Somber Sepulcher without taking a single hit
Defeat Depression without dashing and without getting hit three times
Beat the Calm Caldarium
Beat the Calm Caldarium without taking a single hit
Beat the Ticking Towertop
Beat the Ticking Towertop without taking a single hit
The bedroom door is now permanently opened on Shard 5 and above
Beat the Last Refuge
Beat the Last Refuge without taking a single hit
Uncover the Forgotten Station
Uncover the Void
Unlock your first Soul Gun
Unlock all Soul Gun types
Unlock every single Soul Gun variant
Obtain your first golden Soul Gun
Obtain the golden version of every single Soul Gun variation
Unlock all portal shortcuts at the Technician
Enter a golden rift
Visit a Black Market
Beat a run in under 20 minutes
Beat a run without taking a single hit
Beat a run without picking up any Relics along the way (story relics don't count)
Beat a full run on at least Loop 5
Defeat a boss without shooting once
Unlock all Relics at the Imprisoned
Unlock all expansions at the Tinkerer
Unlock all music pieces from the Fool
Fully complete the Journal
Collect all hats
Free all lost souls
Catch all different types of fish
Obtain every single fishing lure
Unlock all other secrets
Beat a run on Shard 5
Beat a full run on Shard 10
Beat a full run on Shard 20
Beat a full run on Shard 30