Defeat Echino
Defeat Emeraldon Echino
Defeat Magmoth
Defeat Lippyplop
Defeat The Matriarch
Defeat Formless Prime
Defeat 50 Porkos
Defeat 50 Shramplings
Defeat 50 Imperiants
Defeat 50 Emeraldons
Defeat 25 Gloptolisks
Defeat 25 Formless
Defeat 25 Emeraldon Echino Babies
Defeat 25 Cactoid Mamas
Defeat 25 Spore Born
Defeat 50 Weedlings
Defeat 25 Magmoth Babies
Defeat 25 Magflies
Defeat 25 Cactoid Babies
Defeat 25 Imperiant Babies
Activate 25 Beacons
Pick up 100 Shards
Pick up 500 Shards
Pick up 1000 Shards
Pick up 5000 Shards
Pick up 10.000 Shards
Block 100 Attacks
Extract 10 Void Fragments
Extract 25 Void Fragments
Extract 50 Void Fragments
Complete a run
Complete a run on Rogue
Complete a run on Intense
Complete a run on Impossible
Complete a run on Brutal
Unlocked the Void Challenger
Completed the Void Challenge
Get a Stomp Combo of 3
Get a Stomp Combo of 5
Get a Stomp Combo of 10
Get a Stomp Combo of 20
Complete a Loop on 'Rogue' or Higher
Complete Loop 3 on 'Rogue' or Higher
Complete Loop 5 on 'Rogue' or Higher
Complete Loop 3 on 'Impossible'
Unlock the Void Portal
Beat The Void Puppeteer exactly one time
Defeat 50 Voidlings
Defeat 25 Rippers
Defeat 25 Overseers
Defeat 25 Ravagers
Buy out the shop
Buy out the shop 3 times
Unlock Clozo
Unlock all of Clozo's starter weapons
Unlock all of Drash's starter weapons
Unlock Professor Karkamas
Unlock all of professor Karkamas' starter weapons
Unlock Botanika
Unlock all of Botanika's starter weapons
Defeat 25 Tomtos
Defeat 50 Nordunn
Defeat Pony
Defeat 25 Nordunn Elders
Defeat 50 Ugglur
Defeat 25 North Poles
Defeat 25 Greater Pinecrows
Defeat Skogr
Defeat The Prophecy
Fully upgrade a powerup
Clear a Room Challenge
Clear 5 Room Challenges
Clear 15 Room Challenges
Get revived by a Health Ghost
Complete the Ghost Quest
Complete a run in less than 30 minutes
Cause a Beacon to be destroyed
Unlock Doctor Fusion
Unlock all of Doctor Fusion's starter weapons
Create your first pet
Create 5 pets
Create 10 pets
Banish 3 pets
Unlock Karkamas' World Expander
Defeat the Kegler Captain
Defeat 50 Keglers
Defeat Alan Gloob
Defeat 50 Glooboids
Defeat 25 Gloob Crushers
Unlock the Antlantis World Expansion
Unlock the Porko Land World Expansion
Defeat The Harvester
Unlock the North World Expansion
Defeat 50 Junior Harvesters
Defeat 25 Harvest Golems
Unlock every boss essence
Unlock every character essence
Unlock every weapon essence
Unlock every powerup essence
Break a secret crack
Catch the Treasure Guy
Complete the Final Run
Complete 'New Run+'
Complete a Loop on 'New Run+'
Buy out the corrupted shop
Defeat 10 Void Infested Beacons
Complete the Final Run on Impossible
Combine Ice and Fire
Combine Fire and Poison
Combine Water and Ice
Combine Water and Electricity
Combine Gunpowder and Fire
Combine Gunpowder and Electricity
Combine Fire and Wind
Combine Water and Poison
Combine Water and Gunpowder
Combine Water and Wind
Combine Ice and Gunpowder
Combine Ice and Wind
Combine Water and Fire