Complete City - Stage 1

Defeat the city zone boss

Kill 1,000 enemies

Kill 10,000 enemies

Defeat the lab zone boss

Defeat the hell zone boss

Defeat the alien zone boss

Survive the hard route in City Stage 2 without dying

Kill the first boss without killing either turret on the tank on Normal mode or higher

Unlock the laser cannon in Lab Stage 2

Kill the second boss without dying on Normal mode or higher

Destory all alien spaceships in Hell Stage 3

Kill the third boss without killing any lava spitters on Normal mode or higher

Unlock the laser cannon in Mothership Stage 1

Find all the secrets in Mothership Stage 3

Kill the fourth boss with at least 3 slimes still alive on Normal mode or higher

Get a 300 combo

Complete the City Zone without using a single continue on Normal mode or higher

Complete the Lab Zone without using a single continue on Normal mode or higher

Complete the Hell Zone without using a single continue on Normal mode or higher

Complete the Mothership Zone without using a single continue on Normal mode or higher

Complete the entire game without using a single continue on Normal mode or higher

Kill 1000 enemies with the single pistol

Kill 2500 enemies with the dual-pistols

Kill 2500 enemies with the shotgun

Kill 2500 enemies with the machinegun

Kill 2500 enemies with the laser pistol

Kill 2500 enemies with the grenade launcher

Kill 2500 enemies with the flamethrower

Kill 2500 enemies with the chainsaw

Kill 2500 enemies with the laser cannon

Finish a level with 100% accuracy

Get a 200 combo with only the shotgun

Get a 100 combo with only the flamethrower

Kill 8 enemies with one grenade launcher round

Kill 15 enemies with one blast of the laser pistol

Kill 20 enemies at once with the laser cannon

Kill a devil with only the holy cross power-up

Find the secret stash in the Lab Stage 1

Kill 20 enemies by reflecting their own projectiles at them with the reflector shield

Complete the entire City Zone on Hard mode

Complete the entire Laboratory Zone on Hard mode

Complete the entire Hell Zone on Hard mode

Complete the entire Mothership Zone on Hard mode

Complete the game from start to finish with Chainsaw Only mode active from the Secret Options menu on Normal mode or higher