Complete DNA Sequence 6.
Complete Desmond Sequence 4.
Complete DNA Sequence 7.
Complete DNA Sequence 8.
Complete Desmond Sequence 5.
Complete DNA Sequence 9.
Achieve 100% Synchronization in all Sequences.
Complete the Hagia Sofia challenge level.
Collect all Animus data fragments.
Collect all of Ishak Pasha's memoir pages.
Attempt to access DNA Sequence 9 for the first time.
Complete all Bomb Missions.
Complete DNA Sequence 1.
Control all cities (except Rhodes) simultaneously in the Mediterranean Defense game.
Perform a perfect Den Defense without using the cannon.
Climb Hagia Sofia, from the ground to the pinnacle, in under 25 seconds.
Find a secure place to hide and re-enter the Animus.
Complete all Faction Creed Challenges from a single faction.
Get your money back from a Templar tax collector.
Have seven trainees reach the rank of Master Assassin.
Kill 5 guards in 5 seconds using only your hidden blades.
Assassinate 50 guards with the hidden blade.
Parachute onto a zipline.
Collect all available books.
Loot 50 dead guards with thief looting.
Have 10 guards poisoned at the same time.
Kill 5 guards with a scaffold after they have been stunned by caltrops.
Craft 30 bombs.
Have one trainee reach the rank of Master Assassin.
Parachute directly from the top of the Galata Tower to the Golden Horn.
Kill three guards simultaneously with only throwing knives.
Kill 5 guards while under the cover of a smoke screen bomb.
Have a guard incapacitate 3 civilians while he's poisoned.
Find and beat up Duccio.
Complete Desmond Sequence 1.
Complete Desmond Sequence 2.
Complete DNA Sequence 2.
Complete Desmond Sequence 3.
Complete DNA Sequence 3.
Complete DNA Sequence 4.
Complete DNA Sequence 5.
Take the induction leap of faith (The Lost Archive).
Reach the Animus memo (The Lost Archive).
Enter the Animus simulation (The Lost Archive).
Finish memory five (The Lost Archive).
Experience the loop (The Lost Archive).
Find all of the decipher fragments (The Lost Archive).
Break the loop, escape the cycle (The Lost Archive).
Land on a block after falling more than 25 meters (The Lost Archive).
Complete the Animus testing sequence without failing (The Lost Archive).
Make it across the river Styx without failing (The Lost Archive).
Achieve 100% Synchronization in any Sequence other than Sequence 1.
Replay a Memory.
Discover the Shrine in the Catacombe di Roma.
Discover the Shrine in the Terme di Traiano.
Destroy the Machine Gun.
Destroy the Naval Cannon.
Destroy the Bomber.
Destroy the Tank.
Renovate 5 buildings in the Antico district.
Burn All Borgia Towers.
Complete 10 Guild Challenges.
Earn 3 gold medals in the Animus Virtual Training Program.
Recruit 3 Assassins.
Train a recruit up to the Rank of Assassin.
Remove All Borgia Flags in Rome.
Collect All Feathers.
Find 1 Artifact in 2012.
Perform an Execution Streak of 10 kills.
Throw a Long Weapon, Heavy Weapon, and Smoke bomb more than 10 m at a guard.
Kill a guard with a broom.
Win 10,000 florins playing Hazard.
Receive 100% synch in ACB and full synch in all missions of The Da Vinci Disappearance.
Kill 10 guards with a single arrow storm.
Complete The Da Vinci Disappearance.
Beat up the 5 thirsty harlequins.
Double Assassinate from a parachute.
Steal 5 horses from their riders, while remaining on horseback.
Kill a guard with the bag that drops from a lift.
Pay 500 florins to an orator, then pickpocket him afterward.
Throw money in a well.
Jump with the parachute off the top of Castel Sant'Angelo.
Win the highest bet at the Fights.
Access your email in 2012.
Discover the Shrine in Il Colosseo.
Discover the Shrine in the Cloaca Maxima.
Discover the Shrine in Palazzo Laterano.
Discover the Shrine in the Basilica di San Pietro.
Solve all of Subject 16's Puzzles.
Secure the Apple of Eden.
Be reborn as Ezio Auditore da Firenze.
Break out of Abstergo.
Enter the Animus 2.0.
Discover the Assassin's Tomb inside the catacombs under Santa Maria Novella.
Complete training and reenter the Animus.
Complete DNA Sequence 10.
Complete DNA Sequence 11.
Complete DNA Sequence 14.
Escape the hideout.
Find the 8 statuettes in Monteriggioni.
Unlock all 20 pieces of Subject 16's video.
Hide 5 dead bodies in a Bale of Hay.
Kick a guard while using the Flying Machine.
Stun 4 guards at once by throwing sand in their face.
Perform an Air Assassination on a Poisoned NPC.
Kill 10 enemies while remaining in conflict without being hit.
Pickpocket 1000 Florins.
Sprint for 100 meters.
Sweep 5 guards at once by using a Long Weapon.
Discover the Assassin's Tomb inside Santa Maria della Visitazione.
Discover the Assassin's Tomb inside the Torre Grossa.
Discover the Assassin's Tomb inside the Basilica di San Marco.
Discover the Assassin's Tomb inside the Rocca di Ravaldino fortress.
Discover the Assassin's Tomb inside Santa Maria del Fiore (The Duomo).
Complete your first assassination mission for Lorenzo Il Magnifico.
Defend a woman's honor.
Win a race against thieves.
Wear the Auditore cape in each city.
Upgrade a building in the Stronghold.
Synchronize 10 View Points.
Perform a Leap of Faith from the Top of Florence's Giotto's Campanile.
Intercept a Borgia Courrier.
Use your Eagle Vision to scan a Glyph in the environment.
Unlock a piece of Subject 16's video.
Buy a Painting from Florence and Venice.
Reach 80% of your stronghold's total value.
Tint your clothes with those colors: Wetland Ebony and Wetland Ivory.
Collect all the Feathers.
Spend 5000 florins on Courtesans.
Toss more than 300 florins on the ground.
Get all Hidden Blades, Item Pouches and Armor upgrades for Ezio.