You need to die. Just once. It'll be painless.
Unlock the Breakneck Divine Burden.
Unlock the Deadline Divine Burden.
Unlock the Deadly Divine Burden.
Unlock the Eclipse Divine Burden.
Unlock the Excessive Divine Burden.
Unlock the Rebirth Divine Burden.
Unlock the Stout Divine Burden.
Unlock the Unhelpful Divine Burden.
Unlock the portal to the Gardens.
Unlock the portal to the Catacombs.
Unlock the portal to the Palace.
Reach the final Boss Fight.
Complete the game for the first time.
Complete the game without using any wish portals.
Complete the game with all Divine Burdens turned on. No Portals. No Blessings.
Trip, Stun and Disarm the same enemy.
Kill three or more enemies with one Cask of Volatility.
Kill a Silent Effigy.
Disable Etol the Hurler by reflecting its projectile.
Trip 20 enemies by sliding into them.
Find 25 secret rooms.
Use the alternative whip fire to pull away the shields of 10 enemies.
Distract three enemies using one Puzzling Foul.
Die whilst at full health but poisoned.
Unlock the Soldier.
Unlock the Brigand.
Complete the game as The Fool or Traveler.
Complete the game as The Soldier.
Complete the game as The Brigand.
Complete 15 runs as The Fool or Traveler.
Complete 15 runs as The Soldier.
Complete 15 runs as The Brigand.
Equip 9 different swords as The Fool or Traveler.
Hit three different enemies with one sword swing.
Trip 30 enemies using the Hammer of Quaking.
Kill three enemies with one thrown spear.
Recall the spear 20 times.
Kill 10 enemies by pulling out the Pole of Mangling.
Hit the same enemy with all the daggers in a full hand 20 times.
Kill two enemies with one thrown dagger using the Edge of Ricochet.
Freeze 15 enemies using the Skewer of Chilling.
Unlock the Hellion
Complete the game as the Hellion
Complete 15 runs as the Hellion
Disarm 10 enemies with the Cuffs of Disarming
Kill 20 enemies with a fully charged punch.
Kill 15 enemies by punching them into a trap
Unlock the Revenant
Complete the game as the Revenant
Complete 15 runs as the Revenant
Kill three enemies at once with a single Projectile of Ignition
Kill 15 enemies using the Torpedo of Blasting proximity mine
Heal 10 hearts using the Missile of the Leech