ME2: Acquire all trophies

ME2: Save humanity throughout the galaxy from certain annihilation

ME2: Save your crew from an overwhelming attack

ME2: Return to active duty

ME2: Defend a human colony from attack

ME2: Complete the investigation of a derelict alien vessel

ME2: Use the Omega 4 Relay

ME2: Survive suicide mission

ME2: Keep your team alive through the suicide mission

ME2: Obtain geth technology

ME2: Successfully recruit Archangel

ME2: Successfully recruit the Assassin

ME2: Successfully recruit the biotic Convict

ME2: Successfully recruit the Justicar

ME2: Successfully recruit the krogan

ME2: Successfully recruit the Professor

ME2: Successfully recruit the quarian

ME2: Hack a geth collective

ME2: Gain the loyalty of the krogan

ME2: Gain the loyalty of the Assassin

ME2: Gain the loyalty of the biotic Convict

ME2: Help the Justicar resolve her mission

ME2: Gain the loyalty of Archangel

ME2: Gain the loyalty of the Cerberus Operative

ME2: Gain the loyalty of the Professor

ME2: Gain the loyalty of the Cerberus Officer

ME2: Gain the loyalty of the quarian

ME2: Thresher Maw defeated

ME2: Perform 30 headshot kills with any weapon on humanoid targets

ME2: Incinerate the armor of 25 enemies

ME2: Make 20 enemies scream as they fall or are set on fire

ME2: Disrupt the shields of 25 enemies

ME2: Hit 20 different targets with multiple biotic powers to combine the effects

ME2: Warp the barriers of 25 enemies

ME2: Complete 5 missions discovered by scanning unexplored worlds

ME2: Visit 100% of the planets in an unexplored cluster

ME2: Complete a mission discovered by scanning an unexplored world

ME2: Complete any research project in the Normandy's laboratory

ME2: Fully upgrade a weapon

ME2: Unlock 15 new Mass Effect 2 codex entries

ME2: Evolve any power

ME2: Gain the loyalty of the mercenary

ME2: Gain the loyalty of the thief

ME2: Successfully shut down the rogue VI in Project Overlord

ME2: Confront the Shadow Broker