Fully upgrade one weapon.
Purchased every slot in one of the Plasmid or Tonic tracks.
Complete the game on the hardest difficulty setting.
Charged up the Ferris Wheel 9 different times in "A Shocking Turn of Events".
Found all collectable Roses in "A Shocking Turn of Events".
Collect or Invent 53 Tonics in the Physical, Engineering and Combat tracks.
Find every audio diary.
Found all collectable Roses in "The 'I' in Team".
Fully upgrade two weapons.
Shock an enemy in the water.
Fully upgrade five weapons.
Invent all possible ammunication types.
Rescued the Little Sister in "Worlds of Hurt" in under 15:00, on Medium or higher difficulty.
Rescued the Little Sister in "Worlds of Hurt".
Purchase a Plasmid Slot or Tonic Slot in any track.
The player has beaten the game on survivor difficulty.
Fully upgrade three weapons.
Successfully hack a Turret.
Fully upgrade four weapons.
Successfully hack a Security Camera.
Fully research the Houdini Splicer.
The player has taken a picture of Sander Cohen's corpse.
Invent at least one item.
Hit the jackpot at a slot machine.
Successfully hack a security bot.
Either Harvest or Rescue every Little Sister in the game.
Successfully hack a safe.
The player has restored the forests of Arcadia.
Max out all possible research.
The player has completed Sander Cohen's great masterpiece.
Take at least one photo in every research group.
Fully research the Bouncer.
Rescued the Little Sister in "The 'I' in Team" in under 3:00.
Successfully complete 50 hacks.
Fully research the Nitro Splicer.
Fully research the Thuggish Splicer.
Fully research the Spider Splicer.
Rescued the Little Sister in "Worlds of Hurt" using only plasmids, tonics, the wrench, and the research camera, on Medium or higher difficulty.
Complete the game without harvesting any Little Sisters.
Fully research the Rosie.
The player has entered Sander Cohen's personal quarters in Mercury Suites.
Fully research the Leadhead Splicer.
Found all collectable Roses in "Worlds of Hurt".
Successfully complete the Welcome To Rapture Level.
Perform at least one successful hack.
Rescued the Little Sister in "The 'I' in Team" without destroying any Machine Gun Turrets.
The player has defeated Peach Wilkins.
The player has become a Big Daddy.
Take a Research Photo of the highest grade.
Complete the game on Hard difficulty without using a Vita-Chamber.
The player has rescued the Little Sister in "A Shocking Turn of Events" in under 4:00.
Rescued the Little Sister in "A Shocking Turn of Events".
The player has defeated Andrew Ryan.
The player has defeated the crazed J.S. Steinman.
The player has defeated Atlas.
Successfully hack a Vending Machine.
Successfully invent at least 100 items.
Take at least one Research Photo of a Splicer.
Acquire all upgrades for all weapons.
Complete the game on Survivor difficulty without using a Vita-chamber.
Fully research the Little Sister.
Acquire at least one weapon upgrade.
The player has broken Fontaine's mind control.
Rescued the Little Sister in "The 'I' in Team".
Purchase every slot in all four Plasmid and Tonic tracks.