Violate the Pauli exclusion principle.

Kill a bear and eat it. Just eat an entire bear.

Wear your own severed face on your face.

Host three different fungal infections at once.

Project your mind into a goat's body.

Recover the Ruin of House Isner.

Recover Stopsvalinn.

Fall in love with a sign.

Kill a chrome pyramid.

Foresee your own death.

Fall in love with yourself.

Become loved by a faction.

Become hated by the villagers of Joppa.

Become loved by newly sentient beings.

Be crushed under the weight of a thousand suns.

Speak to the alchemist.

Have 10 mutations.

Kill 100 snapjaws.

Perform the introductory water ritual 100 times.

Advance a mutation to level 15.

Learn the complete history of a single sultan.

Activate a time cube.

Wield the amaranthine prism.

Perform the water ritual with Oboroqoru, Ape God.

Kill a trisludge.

Kill a pentasludge.

Kill a decasludge.

Find one of Argyve's old apprentices.

Wield Caslainard and Polluxus.

Make an offering at the Sacred Well of an artifact worth at least 200 reputation.

Convince a frog to teach you how to jump.

Have six arms.

Convince the High Priest of the Stilt to join your party.

Perform the water ritual with Mamon Souldrinker.

Equip the Flume-Flier of the Sky-Bear.

Clone Ctesiphus.

Share the map with 10 clones of yourself.

Share the map with 30 clones of yourself.

Kill Oboroqoru, Ape God.

Recover Kindrish.

Visit 100 generated villages.

Encode the psionic bits of someone's psyche onto the holographic boundary of your own psyche.

Invent 100 recipes.

Successfully cook a meal with neutron flux as an ingredient.

Cook a meal with an extradimensional limb as an ingredient.

Eat the Cloaca Surprise.

Complete the quest What's Eating the Watervine?

Enter 100 giant clams.

Give the repulsive device to all four children of the Tomb.

Help the slynth find a new home.

Be gifted a 10-pointed asterisk.

Exploit wave-particle duality to clone yourself.

Wink out of existence.

Wear each of the six Faces of the sultanate.

Become auroral.

Invoke the Chaos Spiel.

Gain a mutation from a gamma moth's mutating gaze.

Drink 20 drams of brain brine.

Bestow life to 20 inanimate objects.

Tattoo yourself.

Disappoint a highly entropic being.

Recover a relic from a historic site.

Travel to the Six Day Stilt.

Learn a secret from the microbiome.

Have your head explode.

Help Argyve build the contraption.

Return from Golgotha with a repaired waydroid and gain admittance to Grit Gate.

Defeat one of the Girsh nephilim.

Defeat two of the Girsh nephilim in a single playthrough.

Defeat three of the Girsh nephilim in a single playthrough.

Defeat four of the Girsh nephilim in a single playthrough.

Defeat five of the Girsh nephilim in a single playthrough.

Defeat six of the Girsh nephilim in a single playthrough.

Prove the information paradox by causing your surroundings to glitch.

Enter a waking dream from within a waking dream.

Lose your will to live.

Consume 10 drams of sunslag in a single playthrough.

Wake peacefully from twenty dreams.

Smoke from a hookah.

Descend 50 strata deep.

Infiltrate a temple mecha.

Pour a dram of pure warm static on yourself.

Eat the Crystal Delight.

Dash yourself on the crags of spacetime.

Discover 100 lairs.

Eat a serving of humble pie.