Become a mercenary.
Steal the Relic.
Find Alt Cunningham.
Interrogate Anders Hellman.
Talk with Hanako Arasaka.
Complete the main storyline.
Help Takemura avenge the death of Saburo Arasaka.
Leave Night City with the Aldecaldos.
Become a legend of the Afterlife.
Let Johnny Silverhand keep your body.
Complete River Ward's storyline.
Complete Kerry Eurodyne's storyline.
Complete Judy Alvarez's storyline.
Complete Panam Palmer's storyline.
Watch Bushido X with Rogue.
Collect all items that once belonged to Johnny Silverhand.
Complete all gigs and NCPD Scanner Hustles in Watson.
Complete all Cyberpsycho Sightings.
Complete all gigs and NCPD Scanner Hustles in Pacifica.
Complete all gigs and NCPD Scanner Hustles in the Badlands.
Complete all gigs and NCPD Scanner Hustles in Westbrook.
Complete all gigs and NCPD Scanner Hustles in Heywood.
Complete all gigs and NCPD Scanner Hustles in Santo Domingo.
Complete all gigs and NCPD Scanner Hustles in City Center.
Install at least one implant in each system and body part.
Kill or incapacitate 3 enemies in quick succession with a revolver or pistol in close combat.
Complete a Breach Protocol with a minimum of 3 daemons uploaded.
Reach the max level in any skill.
Shoot an enemy grenade in midair with a revolver.
Kill or incapacitate 2 enemies with the same sniper rifle shot.
While Berserk cyberware is active, perform a Superhero Landing to kill or incapacitate 2 enemies.
Use a dialogue option related to V's life path 10 times.
Buy all vehicles available for purchase.
Craft 3 Legendary items.
Kill or incapacitate 3 enemies with one "Detonate Grenade" quickhack.
Kill or incapacitate 50 enemies while time is slowed.
Perform the Distract Enemies quickhack 30 times without drawing attention to yourself.
After reviving with Second Heart, kill or incapacitate the enemy who killed you within 5 seconds.
Kill or incapacitate 300 enemies using ranged weapons.
Kill or incapacitate 100 enemies using melee weapons.
Kill or incapacitate an enemy who threw a grenade at you.
Find all the tarot graffiti for the job Fool on the Hill.
Find all fast travel dataterms.
Reach max Street Cred.
Fulfill Songbird's request.
Refuse Songbird's request.
Take Songbird to the stars.
Take Songbird home.
Complete "Things Done Changed".
Complete “Run This Town”.
Save President Myers.
Complete every Gig in Dogtown.
Eliminate three bosses from the "Increased criminal activity" category.
Steal the Arasaka medical truck or deliver 10 vehicles to El Capitan.
Defeat the Chimera.
Unlock all Perks in the Relic Perk tree.
Become Dogtown's most wanted criminal.