Complete the game on Human mode.
Complete the game on Devil Hunter mode.
Complete the game on Son of Sparda mode.
Complete the game on Dante Must Die mode.
Complete the game on Heaven or Hell mode.
Complete the game on Hell and Hell mode.
Clear the Prologue Mission.
Defeat all enemies in Mission 01.
Collected Red Orbs from an unexpected spot in Mission 02.
Clear Mission 03.
Destroy a certain wall in Mission 04.
Fend off a menace from above in Mission 05.
Clear Mission 06.
Clear Mission 07 with both Nero and V.
Clear Mission 08.
Destroy a certain wall in Mission 09.
Clear Mission 10.
Use proper timing to get a leg up in a close-quarters battle against the boss in Mission 11.
Clear Mission 12.
Clear Mission 13 with Nero, V, and Dante.
Clear Mission 14.
Proceed with caution and avoid unneeded damage in Mission 15.
Go on the offensive without relying on brute force in the Mission 16 boss battle.
Clear Mission 17.
Clear Mission 18.
Clear Missions 19 and 20 without using continues (any difficulty except Heaven or Hell).
Perform a Stylish Rank S combo.
Perform a Stylish Rank SS combo.
Perform a Stylish Rank SSS combo.
Clear all secret missions.
Defeat 5 enemies in 1 second.
Wield overwhelming power to exact an unexpected conclusion.
Clear all missions with S rank.
Clear all missions with S rank on all difficulties except Heaven or Hell.
Rack up a total of 60 minutes in the air by jumping or other means.
Acquire all of Nero's skills.
Acquire all of Dante's skills.
Acquire all of V's skills.
Upgrade your vitality gauge to max.
Upgrade your Devil Trigger Gauge to max.
Accept a new job from Morrison after the Red Grave incident.
Collect more than 1,000,000 Red Orbs total.
Defeat 1,000 enemies total.
Collect more than 100 Devil Breakers during missions.
Use more than 500,000 Red Orbs total with Dr. Faust.
Clear Mission 11 without equipping a weapon set for Dante (any difficulty except Heaven or Hell).
Beat Mission 07 without any starting Devil Breakers equipped (any difficulty except Heaven or Hell).
Clear Mission 05 without V's demons getting stalemated (any difficulty except Heaven or Hell).
Clear all missions as Vergil.
Acquire all of Vergil's skills.
Clear Mission 19 as Vergil without using any weapons other than Yamato. (Heaven or Hell excluded)
Clear the Bloody Palace as Vergil.
Clear the Bloody Palace with Nero.
Clear the Bloody Palace with Dante.
Clear the Bloody Palace with V.