Defeat General Tygo.

Defeat General Renzo.

Defeat Dessa.

Defeat the Three Brothers.

Defeat Coach Fredrick.

Defeat Dr. Michaels.

Defeat the Sightless All-Star.

Discovered every region.

Obtain all Primary Weapons.

Obtain all Secondary Weapons.

Defeat the Salvager.

Defeat the Three Sisters.

Defeat the Benchwarmer.

Unlocked all Abilities.

Defeat your Nightmare.

Defeat the Document Eater.

Defeat the Document Dissolver.

Find all health upgrades.

Defeat the Berserk Executive.

Defeat General Dau.

Find the hidden gym and go a few rounds with a peculiar Possessor.

Locate the hidden lobsters.

Defeat Mr. Demars.

Defeat General Moja.

Obtained all achievements.

Obtain all Affixes.

Fully upgrade your meds.