[Jill] Collect the Book of Curse

[Jill] Collect your prize from the Bathtub

[Jill] Get saved from fitting nicely into a sandwich by Barry

[Jill] Obtain the Shotgun without Barry's help

[Jill] Obtain the Grenade Launcher

[Jill] Collect the Armor Key

[Jill] In the Fish Tank Room, blow up the Bee with a Grenade

[Any Character] Kill the Plant in the Mansion Greenhouse without destroying the Herbs

[Jill] Obtain the Shield Key

[Jill] Defeat Yawn during your first encounter

[Jill] Save Richard...and then collect his Assault Shotgun when he dies anyway...

[Jill] Place the Death Masks and kill the Crimson Head that emerges from the coffin

[Jill] Escape from Lisa Trevor's cabin

[Any Character] Escape from Lisa Trevor's cabin without taking damage

[Jill] Use the Self Defense Gun to kill the Zombie in Room 001

[Any Character] Kill the smaller Sharks in the Aqua Ring Walkway before draining the water

[Jill] Fry Neptune

[Jill] Have Barry kill Plant 42 for you

[Jill] Kill Plant 42 by yourself

[Jill] Kill Yawn in the Mansion Library

[Jill] Obtain the Magnum

[Jill] Watch Enrico die, then check his body

[Jill] Kill Black Tiger

[Any Character] Escape from Black Tiger's room without killing it or any other spiders

[Jill] Collect Barry's Magnum

[Jill] Save Barry's life...and then watch him die by Lisa's hand anyway

[Any Character] Kill Yawn in the Mansion Library without taking damage

[Jill] Give Lisa her mother back

[Jill] Take care of Lisa without pushing down any of the concrete slabs

[Jill] Kill the Tyrant...maybe?

[Jill] Complete the game without saving anyone

[Any Character] Kill the Tyrant and escape the Mansion after watching it kill your partner

[Jill] Save Chris

[Jill] Complete the game having saved both Barry and Chris

[Any Character] In one session, kill 5 enemies using the Survival Knife, without unequipping it (resets upon returning to main menu)

[Any Character] In one session, kill 20 enemies with the Handgun (resets upon returning to main menu)

[Any Character] In one session, kill 20 enemies with the Shotgun (resets upon returning to main menu)

[Any Character] In one session, kill 20 enemies with the Assault Shotgun (resets upon returning to main menu)

[Jill] In one session, kill 20 enemies with the Grenade Launcher (any rounds) (resets upon returning to main menu)

[Any Character] In one session, kill 10 enemies with the Magnum Revolver (resets upon returning to main menu)

[Jill] In one session, kill 5 enemies with Barry's .44 Magnum (resets upon returning to main menu)

[Any Character] In one session, kill 30 enemies with the Samurai Edge (resets upon returning to main menu)

[Any Character] In one session, kill 40 enemies with the Infinite Rocket Launcher (resets upon returning to main menu)

[Chris] Return to the Main Hall and find that everybody's gone

[Chris] Blow the Dog Whistle and successfully take the collar from the Cerberus that answers the call

[Any Character] Unlock all Sword Key doors

[Any Character] Unlock all Armor Key doors

[Chris] Put down Forest after he reanimates as a zombie

[Chris] Help Rebecca save Richard by getting him medicine

[Chris] Find Richard dead because you recklessly took too much time finding him medicine

[Chris] Obtain the Shotgun

[Chris] Watch Rebecca perform a piano solo for you

[Chris] Complete the Armor Room Puzzle and collect the box

[Chris] Complete the Gallery Puzzle and collect the Death Mask behind it

[Chris] Kill the plant guarding a Death Mask and then collect it

[Chris] Defeat Yawn during your first encounter

[Rebecca] Save Chris after he gets poisoned by Yawn

[Rebecca] Save Chris from the poison within 40 seconds

[Any Character] During the first Yawn encounter, grab the Death Mask and leave the room without killing Yawn, taking damage or running away (must NOT have saved Richard as Jill)

[Chris] Escape from Lisa Trevor's cabin

[Any Character] Drain the water in the Aqua Ring with the Critical percentage reaching no higher than 30%

[Chris] Kill Neptune

[Chris] Take Richard's Assault Shotgun after draining the water

[Any Character] Kill the first Zombie with an Infinite Weapon. Infinite Weapon unlocks will block all progression achievements and some challenges. All achievements must also be earned on Normal Difficulty or higher. Read forum topic for more info.

[Jill] Destroy the Beehive in the Guardhouse

[Chris] Kill Plant 42 after Rebecca uses the V-Jolt to weaken it

[Chris] Kill Plant 42 by yourself

[Rebecca] Put down a shark that's flopping around out of water

[Any Character] Kill Plant 42 without using the V-Jolt and without taking damage or running away

[Chris] Unlock all simple locks using Old Keys

[Chris] Kill Yawn in the Mansion Library

[Any Character] Unlock all Helmet Key doors

[Chris] Save Rebecca from the Hunter that attacks her in the Small Library

[Chris] Reach the Small Library before the Hunter kills Rebecca...then watch her die anyway...

[Chris] From the moment Rebecca is first attacked by the Hunter, reach the Small Library within 10 seconds

[Chris] Obtain the Magnum

[Chris] Collect the Flamethrower

[Chris] Kill Black Tiger

[Chris] Kill Black Tiger using only the Flamethrower and without taking damage or running away (must enter room with Flamethrower equipped)

[Chris] Get the elevator in the underground caverns working...and venture into Lisa's territory...

[Chris] Assist Wesker in giving Lisa some closure

[Chris] Allow Lisa to take out Wesker

[Chris] Assist Wesker in forcibly laying Lisa to rest, without touching those worthless concrete slabs...

[Any Character] Watch Kenneth's final moments

[Chris] Defeat the Tyrant after it kills Wesker...maybe?

[Chris] Save Jill

[Chris] Complete the game without saving anyone

[Chris] Complete the game having saved both Rebecca and Jill

[Any Character] Collect all Files and Maps in the game (excluding Barry's Photograph)

[Any Character] Kill all Cerberus in the game

[Any Character] Kill all Hunters in the game (not counting those that are exclusive to Chris)

[Any Character] Kill all Web Spinners in the game

[Any Character] Kill all Crows in the game

[Any Character] Kill all Chimera in the game

[Any Character] Kill the Tyrant at the Heliport without taking damage and without letting your partner get killed

[Chris] Complete the game in under 3 hours

[Jill] Complete the game in under 3 hours

[Any Character] Grab the Gallery Key and escape the Water Tank without killing Neptune

[Chris] Complete the game on Hard Difficulty (Final Boss Required)

[Jill] Complete the game on Hard Difficulty (Final Boss Required)

[Chris] Complete the game on Real Survival (Final Boss Required)

[Jill] Complete the game on Real Survival (Final Boss Required)

[Chris] Complete the game on Invisible Enemy (Final Boss Required)

[Jill] Complete the game on Invisible Enemy (Final Boss Required)

[Any Character] Complete the game with One Dangerous Zombie active (Final Boss Required)

[Any Character] Complete the game without saving (Final Boss Required)

[Any Character] Complete the game in one session using no weapons other than the Knife

[Any Character] Complete Invisible Enemy without saving on Hard Difficulty (Final Boss Required)

[Any Character] Earn the personal admiration of Mikami-san! (finish Invisible Enemy in under 5 hours)

[Any Character] Use the Closet Key and change your costume

[Chris] Complete the game in one session without using an Item Box (must NOT be playing Real Survival)

[Jill] Complete the game in one session without using an Item Box (must NOT be playing Real Survival)

[Any Character] Land the finishing blow on the Tyrant in the Laboratory using the Self-Defense Gun

[Any Character] Blow the Dog Whistle and retrieve the Collar without taking damage or leaving the balcony.