Enter the Web-Head: Listen to all of Beasts 'practical' and 'necessary' pointers

Burglary Interrupted: Shoot some B-Ball

Rooftops By Night: Defeat all 21 enemies without taking damage

Warehouse 66: Take out all enemies from the ceiling without taking damage

Spidey Vs. Shocker: Defeat The Shocker

Spidey Vs. Shocker: Defeat The Shocker with only two hits without taking damage

Smoke Screen: Collect all 4 keys before using any of them and defuse the bomb on Normal or higher difficulty

Hangar 18: Take out all enemies and machine guns without setting off your spider-sense

Wind Tunnel: Make the plane make a full circle without crashing into anything

To Catch a Thief: Catch up to the chopper in 2:00 or less

In Darkest Night: Complete the train yard puzzle using only 3 switches

Heart of Darkness: Put 10 enemies on ice

Catch That Train!: Catch up to the train and meet up with a fellow bug

Catch That Train!: Catch the train without taking damage or damaging Sandman

Gangland: Take out all the gangsters and rescue all the hostages without taking damage

Spidey Vs. Hammerhead: Defeat Hammerhead

Spidey Vs. Hammerhead: Defeat Hammerhead without taking damage

Spidey in the Machine: Complete the actuator puzzle in 5 seconds

Mission: Spidey: Complete the impossible mission without taking damage at all

The Corkscrew: Carefully make your way up the shaft without taking damage

Spidey Vs. Lizard: Defeat the Lizard and rescue your old pal, Dr. Connors

Spidey Vs. Lizard: Defeat the Lizard using only the serum without taking damage on normal or higher difficulty

The Gauntlet: Disable all 13 laser turrets with electric webbing then destroy them with melee attacks

Spidey Vs. Sandman Again: Defeat the Sandman

Spidey Vs. Sandman Again: Defeat the Sandman without taking damage and without missing him with a water spray

Konichi-Wa, Spider-San: Destroy the generator in 3:00 or less

Rock of Ages: Scale the wall without stopping or taking damage

Spidey Vs. Electro: Defeat Electro's first form without taking damage

The Best Laid Plans: Defeat Electro's final form without taking damage, stunning him no more than 6 times

Help Thor save the world!

What if Spider-Man rode the banana?

What if Spider-Man defeated 10 enemies in warehouse 66 without webbing or melee attacks?

What if Spider-Man was good at pong?

What if Spider-Man broke the machine?

Complete the Web-Slinging Challenge in 1:10.0 or less

Complete the Web Yank Challenge in 0:25.0 or less

Complete the L1 Targeting Challenge in 0:30.0 or less

Complete the L2 Targeting Challenge with a score of 140 or better

Complete the Zip-Line Challenge in 1:30.0 or less

Complete the Stealth Challenge in 1:15.0 or less

Defeat 75 Thugs in the Attack Challenge

Defeat Electro once and for all as Spider-Phoenix

Defeat Shocker as Prodigy

Clear out Warehouse 66 as Dusk

Complete Mission: Spidey using the insulated suit

Interrupt a burglary with the Red Alex Ross suit

Catch a thief with the White Alex Ross suit

Defeat the Lizard as Venom 2 - Earth X

Wind your way up The Corkscrew in the Negative Zone suit

Defeat Electro in the Museum as Symbiote Spider-Man

Complete Spidey in the Machine as Spider-Man 2099

Defeat the Sandman as Captain Universe

Get inside Hangar 18 as Spidey Unlimited

Scale the Rock of Ages as The Amazing Bag Man!

Defeat Hammerhead as Scarlet Spidey

Catch That Train as Ben Reily

Stop the plane as Quick Change Spidey

Complete The Gauntlet as Peter Parker

Complete Enter the Web-Head as Battle-Damaged Spidey

Create an overpowered Spider-Suit

Remember kids, only cheaters use bad words!

Unlock all Bugle Headlines

Unlock all of Parker's Portfolio

Collect all comics

Unlock all costumes

Complete the game on Hard difficulty