Complete "Feel the Burn"
Complete "Life in the Big City"
Complete "H-Bombers Shakedown"
Complete "Breaking News"
Complete "Cold-Blooded Candids"
Complete "A Harry Situation"
Complete "Crank Collar"
Complete "Reptilian Rampage"
Complete "Escape Under New York"
Complete "Hunter or Hunted?"
Complete "Rumble Down Under"
Complete "The Unusual Suspects"
Complete "The Cornered Animal"
Complete "My, What Big Teeth You Have"
Complete "Lizard Leftovers"
Complete "Wild Bat Chase"
Complete "By the Dawn's Early Light"
Complete "Crowd Control"
Complete "Tribal Takedown"
Complete "Family Reunion"
Complete "Stunt Double"
Complete "My Way or the Subway"
Complete "My Dinner with MJ"
Complete "The Final Showdown"
Collect all 50 Spider Emblems
Collect all 100 Meteorite Fragments
Purchase all Hero Upgrades
Complete every Trick Race with the rank of Super Hero
Deactivate all 7 bombs in "Breaking News" in under 55 seconds
Complete "A Harry Situation" without taking damage more than 3 times
Escape the giant drill in "Hunter or Hunted?" without taking damage
[City Alert] Help deliver some delicious Fruit Pies
[City Alert] Perform some stunts for a tourist's camera
Reduce ALL gang activity to 0%
Reduce Apocalypse gang activity to 0%
Reduce H-Bombers gang activity to 0%
Reduce Dragon Tails gang activity to 0%
Reduce Waste Tribe gang activity to 0%
Keep a combo going for 20 hits or more
Deal 2000 damage or more during a combo and earn a "SENSATIONAL" score
Take all 35 Villain Photos
Defeat Venom for the first time in "The Final Showdown" with at least 2 minutes left on the clock
Destroy three generators in "My, What Big Teeth You Have" without taking damage
Survive until dawn in "By the Dawn's Early Light" without deploying more than 3 web traps
Defeat Shriek in "Crowd Control without pressing the X button or taking damage more than 5 times
Reach 100% completion percentage
[City Alert] Help find a lost child
[City Alert] Escort a journalist to an important news story
Purchase all Health Upgrades
Purchase all Speed Upgrades