Purchase all upgrades for Prowler
Purchase all upgrades for Black Cat
Purchase all upgrades for Doc Ock
Purchase all upgrades for Green Goblin
Purchase all upgrades for Scorpion
Purchase all upgrades for Iron Fist
Purchase all upgrades for Rhino
Purchase all upgrades for Lizard
Purchase all upgrades for Sandman
Purchase all upgrades for Blade
Purchase all upgrades for Venom
Purchase all upgrades for Spider-Man
Purchase all upgrades for New Goblin
Collect every DNA helix located in Tokyo
Collect every DNA helix located on Tangaroa Island
Collect every DNA helix located in Egypt
Collect every DNA helix located in Transylvania
Collect every DNA helix located in Nepal
Complete every arena located in Tokyo
Complete every arena located on Tangaroa Island
Complete every arena located in Egypt
Complete every arena located in Transylvania
Complete every arena located in Nepal
Complete the Industrial Plant mission, in Tokyo
Complete the Secret Lab mission, in Tokyo
Complete the Rooftops mission, in Tokyo
Complete the Oscorp Japan mission, in Tokyo
Complete the Beachside mission, on Tangaroa Island
Complete the Sea Caves mission, on Tangaroa Island
Complete the Cliffs mission, on Tangaroa Island
Complete the Ancient Ruins mission, on Tangaroa Island
Complete the Sun-Drenched City mission, in Egypt
Complete the Oasis mission, in Egypt
Complete the Unearthed Catacombs mission, in Egypt
Complete the Excavation Site mission, in Egypt
Complete the Oldworld Village mission, in Transylvania
Complete the Manor House mission, in Transylvania
Complete the Graveyard Path mission, in Transylvania
Complete the Ancient Church mission, in Transylvania
Complete the Lower Village mission, in Nepal
Complete the Dark Caverns mission, in Nepal
Complete the Upper Village mission, in Nepal
Complete the Temple mission, in Nepal
Purchase all upgrades for Web Line
Purchase all upgrades for Web Shoot
Purchase all upgrades for Web Stun
Reach a hit chain of 20 or more in any mission
Complete any mission in Tokyo with Spider-Man's combo meter at level 4
Complete any mission on Tangaroa Island with Spider-Man's combo meter at level 4
Complete any mission in Egypt with Spider-Man's combo meter at level 4
Complete any mission in Transylvania with Spider-Man's combo meter at level 4
Complete any mission in Nepal with Spider-Man's combo meter at level 4