Rescue the hostages and safely dispose of the bomb

Resolve the hostage situation and stop the bomb without taking damage

Defeat 14 enemies while 'racing' to the Bugle

Defeat Scorpion and rescue Jameson! Because... Reasons

Defeat Scorpion without Spidey or Jameson taking damage and without letting Scorpion find Jameson

Reach the top of the building on the Missile Attack level without stopping or taking damage

Locate the Green Goblin's lair

Complete all five levels of the police chase without attacking any cops

Defeat Rhino

Destroy all four transformers and defeat Rhino without taking damage

Defeat Venom for the first time

Defeat Venom for the first time without throwing a single punch or kick or being grabbed by Venom

Knock 25 lizardmen off the subway car

Find the Lizard in the maze

Reach the end of the Lizard's maze in less than 50 seconds

Defeat Venom again and rescue your wife... again

Defeat Venom without taking damage or allowing the water flow to be turned back on

Locate the spidey armor in the elevator shaft

Find three magnesium cartridges in the Bugle's Basement

Defeat Mysterio and find out what this has all been about

Defeat Mysterio while missing no more than three shots with your impact webs

Collect the hidden Spidey armor in the waterfront warehouse ventilation shaft

Cross the Underwater Trench without taking damage (Normal or higher difficulty)

Defeat Doc Ock

Defeat Doc Ock without taking damage before his shield can regenerate for a second time on Easy or Normal difficulty

Defeat Carnage

Defeat Carnage without letting him get off a single attack

Escape from Monster Ock and save the world! ... Again

What if one of the Fantastic Four was around?

What if Peter Parker could bust a move?

What if Spider-Man didn't save Jameson?

What if Spider-Man hitched a ride on a blimp?

What if Spider-Man annoyed the Lizard?

What if Spider-Man activated all four switches and drowned his wife?

What if Spider-Man found his impostor?

What if Spider-Man raided the lost ark?

What if Spider-Man won a race against a yellow submarine? (Normal or higher difficulty)

What if Black Cat got footloose?

What if Doc Ock was only 6 inches tall?

What If Venom's prime suspect was guilty?

Take out 15 Lizardmen in Time Attack Training

Survive for 3:00 against the symbiotes in survival training

Complete Speed Training 1 in less than 0:40

Complete Speed Training 2 in less than 1:30

Complete Speed Training 3 in less than 0:45

Score 18 points in Target Practice

Complete Item Hunt training in less than 1:10

Earn 10,000 points in Zip-Line training

Rescue all the hostages in the Daily Bugle and defeat Mysterio as Spider-Man 2099

Make your way through the sewers, defeat Venom and rescue Mary Jane as Symbiote Spider-Man

Defeat the three final bosses as Captain Universe

Rescue the hostages in the bank and defuse the bomb as Spidey Unlimited

Defeat Rhino as Scarlet Spidey

Infiltrate the Waterfront Warehouse and rescue Black Cat as the Amazing Bag Man!

Catch Venom and kick the crap out of him as Ben Reilly

Escape the Cops as Quick-Change Spidey

Race to the Bugle and rescue Jameson as Peter Parker

Collect all comics

Unlock All Costumes

Complete the game on Hard difficulty