Call Mister Fantastic.
Find a bonus in stage 1.
Get the white suit.
Have 20 Spider Lives.
Clear stage 2 (no level select).
Clear stage 1 (no level select).
Defeat stage 1 boss without losing a spider life.
Clear Stage 3 (no level select).
Defeat stage 2 boss without losing a spider life.
Clear stage 4 (no level select).
Defeat stage 4 boss without losing a spider life.
Find a bonus in stage 4.
Call the Human Torch.
Call the Thing.
Call the Invisible Woman.
Defeat Venom and beat the game (no level select).
Find a bonus in stage 2.
Find a bonus in stage 5.
Clear stage 5 (no level select).
Clear the game on Spectacular Mode (no level select).
Clear the game in under 1 hour and 10 minutes (Pause doesn't count).
Defeat stage 5 boss without losing a spider life.
Find a secret room in the bonus (Spectacular Mode Only)